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Joanna is a leading actress in the West End & on the international stage. Kim in Miss Saigon (London, original Australian production, original United Kingdom & Ireland Tour & 10th Anniversary Performance), Mary Magdalene in the West End revival of Jesus Christ Superstar (London), Éponine in Les Misérables (London & Odyssey Arena Belfast Concert), Fantine in Les Misérables (London & Windsor Concert performed for HM Queen Elizabeth II & the Royal Family), Grizabella in Cats (London, UK, European, Middle Eastern, Asian & 40th Anniversary Tours), Mimi in Rent (European Tour), Christmas Eve in Avenue Q (London), Sheila Franklin in Hair (London), Thanh in the world premiere of The Real Love (Los Angeles), Heidi in I Sing! (London), Ingenue June in the West End premiere of The Musical of Musicals The Musical! (London), Francesca Johnson in the international premiere of The Bridges of Madison County (Manila), Inang Bayan in Rebel (Manila), Maria in West Side Story (Manila), Maria Von Trapp in The Sound of Music (Manila), The Magic of Disney in Concert (London), Nellie Forbush in South Pacific (Manila), Blue Fairy in Pinocchio: A New Musical (Singapore), West End Women (UK Tour), Defying Gravity: The Songs of Stephen Schwartz (Sydney), Mary Magdalene in Jesus Christ Superstar in Concert (Tokyo), Bloody Mary in South Pacific (Chichester, London & UK Tour), & Jenna in the international premiere of Waitress (Manila).

She can be seen in the television & digital series Call Me Tita (Netflix/iWant), Babae Sa Septic Tank 3 (Netflix/iWant), Flower of Evil (Viu/iWant)The Quest (BBC), Broken News (BBC), & Mummy Autopsy (Discovery Channel). She portrayed Corazon in Maalaala Mo Kaya's "Kadena" (iWant)  winning the GEMS Award for Best Actress for Television.

She portrayed Candida in the feature film Ang Larawan/The Portrait (Netflix), winning the 2017 Metro Manila Film Festival (MMFF), PMPC Star Awards, Gawad Pasado, Luna, Gawad Tangi, Guillermo Award, Urduja Best Heritage Film Awards & the Gawad Urian Awards for Best Actress.

She can be heard on the cast recordings of Miss Saigon (The Complete Symphonic Recording) as Kim, Jesus Christ Superstar (London Revival Castas Mary Magdalene, the concept cast recording of The Postman and the Poet (Concept Album) as Beatriz Gonzalez & the feature film Ang Larawan (Original Soundtrack) as Candida Marasigan. Her debut album Joanna Ampil was recorded in Abbey Road Studios (JAY Records), followed by pop albums Try Love (Sony Music) & Joanna Ampil (VIVA Records). Recordings including her singles Always Better, Memory & One More Gift are all available for streaming on Apple Music & Spotify.

She performed Grizabella in the 40th Anniversary Tour of Catduring the height of the COVID-19 pandemic & at one point the only performing theatrical production in the whole world. This is chronicled in the new documentary film The Show Must Go On (AppleTV+).

In 2023, she starred as the first female The Engineer in a historic brand new production of Miss Saigon at The Crucible (Sheffield Theatres) in the United Kingdom.

Joanna joined international stars of the stage & screen Michael Ball, Daniel Dae Kim, Maria Friedman, Audra McDonald, Julian Ovenden, Lucy St. Louis, Aaron Tveit, Marisha Wallace,Patrick Wilson in My Favorite Things: The Rodgers & Hammerstein 80th Anniversary Concert, featuring a 40-piece orchestra on 12 December 2023, at the Theatre Royal Drury Lane. It will be screened in cinemas across the UK, Ireland, Australia, New Zealand, and North America, and will be part of the Great Performances (PBS) broadcast this Spring 2024.

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